MST4 kinase phosphorylates ACAP4 protein to orchestrate apical membrane remodeling during gastric acid secretion

Digestion in the stomach depends on acidification of the lumen. Histamine-elicited acid secretion is triggered by activation of the PKA cascade, which ultimately results in the insertion of gastric H,K-ATPases into the apical plasma membranes of parietal cells. Our recent study revealed the function...

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Vydáno v:J Biol Chem
Hlavní autoři: Yuan, Xiao, Yao, Phil Y., Jiang, Jiying, Zhang, Yin, Su, Zeqi, Yao, Wendy, Wang, Xueying, Gui, Ping, Mullen, McKay, Henry, Calmour, Ward, Tarsha, Wang, Wenwen, Brako, Larry, Tian, Ruijun, Zhao, Xuannv, Wang, Fengsong, Cao, Xinwang, Wang, Dongmei, Liu, Xing, Ding, Xia, Yao, Xuebiao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625048/
https://ncbi.nlm.nih.gov/pubmed/28808054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808212
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