Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity

Variants in CNTNAP2, a member of the neurexin family of genes that function as cell adhesion molecules, have been associated with multiple neuropsychiatric conditions such as schizophrenia, autism spectrum disorder and intellectual disability; animal studies indicate a role for CNTNAP2 in axon guida...

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Bibliografiska uppgifter
I publikationen:NPJ Schizophr
Huvudupphovsmän: Flaherty, Erin, Deranieh, Rania M., Artimovich, Elena, Lee, Inkyu S., Siegel, Arthur J., Levy, Deborah L., Nestor, Michael W., Brennand, Kristen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Brief Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624885/
https://ncbi.nlm.nih.gov/pubmed/28970473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41537-017-0033-5
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