Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA (Kera(RT)), for Corneal Stroma and Tendon Research

PURPOSE: We created a novel inducible mouse line Keratocan-rtTA (Kera(RT)) that allows specific genetic modification in corneal keratocytes and tenocytes during development and in adults. METHODS: A gene-targeting vector (Kera- IRES2-rtTA3) was constructed and inserted right after the termination co...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Zhang, Yujin, Kao, Winston W.-Y., Hayashi, Yasuhito, Zhang, Lingling, Call, Mindy, Dong, Fei, Yuan, Yong, Zhang, Jianhua, Wang, Yen-Chiao, Yuka, Okada, Shiraishi, Atsushi, Liu, Chia-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Cornea
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624774/
https://ncbi.nlm.nih.gov/pubmed/28973326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22661
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