LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination

The regulation of inflammation is pivotal for preventing the development or reoccurrence of multiple sclerosis (MS). A biased ratio of high‐M1 versus low‐M2 polarized microglia is a major pathological feature of MS. Here, using microarray screening, we identify the long noncoding RNA (lncRNA) GAS5 a...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Sun, Dingya, Yu, Zhongwang, Fang, Xue, Liu, Mingdong, Pu, Yingyan, Shao, Qi, Wang, Dan, Zhao, Xiaolin, Huang, Aijun, Xiang, Zhenghua, Zhao, Chao, Franklin, Robin JM, Cao, Li, He, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623836/
https://ncbi.nlm.nih.gov/pubmed/28808113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643668
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