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Single nucleotide variations in cultured cancer cells: effect of mismatch repair

We assessed single nucleotide variations (SNVs) between individual cells in two cancer cell lines; DU145, from brain metastasis of prostate tumor with deficient mismatch repair; and HT1080, a fibrosarcoma cell line. Clones of individual cells were isolated, and sequenced using Ion Ampliseq comprehen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mutat Res
Egile Nagusiak: Panyutin, Igor G., Panyutin, Irina V., Powell-Castilla, Ian, Felix, Laura, Neumann, Ronald D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623640/
https://ncbi.nlm.nih.gov/pubmed/28837838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2017.07.003
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