pIL6-TRAIL-engineered umbilical cord mesenchymal/stromal stem cells are highly cytotoxic for myeloma cells both in vitro and in vivo

BACKGROUND: Mesenchymal/stromal stem cells (MSCs) are favorably regarded in anti-cancer cytotherapies for their spontaneous chemotaxis toward inflammatory and tumor environments associated with an intrinsic cytotoxicity against tumor cells. Placenta-derived or TRAIL-engineered adipose MSCs have been...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Cafforio, Paola, Viggiano, Luigi, Mannavola, Francesco, Pellè, Eleonora, Caporusso, Concetta, Maiorano, Eugenio, Felici, Claudia, Silvestris, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622499/
https://ncbi.nlm.nih.gov/pubmed/28962646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0655-6
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