Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

BACKGROUND: Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets. METHODS: Human MSC and human islets (or pseudoislets, obtained...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Montanari, Elisa, Meier, Raphael P. H., Mahou, Redouan, Seebach, Jörg D., Wandrey, Christine, Gerber-Lemaire, Sandrine, Buhler, Leo H., Gonelle-Gispert, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622460/
https://ncbi.nlm.nih.gov/pubmed/28962589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0646-7
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