Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

BACKGROUND: Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets. METHODS: Human MSC and human islets (or pseudoislets, obtained...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Montanari, Elisa, Meier, Raphael P. H., Mahou, Redouan, Seebach, Jörg D., Wandrey, Christine, Gerber-Lemaire, Sandrine, Buhler, Leo H., Gonelle-Gispert, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622460/
https://ncbi.nlm.nih.gov/pubmed/28962589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0646-7
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