α(V)β(3) Integrin regulates astrocyte reactivity

BACKGROUND: Neuroinflammation involves cytokine release, astrocyte reactivity and migration. Neuronal Thy-1 promotes DITNC1 astrocyte migration by engaging α(V)β(3) Integrin and Syndecan-4. Primary astrocytes express low levels of these receptors and are unresponsive to Thy-1; thus, inflammation and...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Lagos-Cabré, Raúl, Alvarez, Alvaro, Kong, Milene, Burgos-Bravo, Francesca, Cárdenas, Areli, Rojas-Mancilla, Edgardo, Pérez-Nuñez, Ramón, Herrera-Molina, Rodrigo, Rojas, Fabiola, Schneider, Pascal, Herrera-Marschitz, Mario, Quest, Andrew F. G., van Zundert, Brigitte, Leyton, Lisette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622429/
https://ncbi.nlm.nih.gov/pubmed/28962574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0968-5
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