Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

Alcohol consumption has been linked to over 200 diseases and is responsible for over 5% of the global disease burden. Well-known genetic variants in alcohol metabolizing genes, for example, ALDH2 and ADH1B, are strongly associated with alcohol consumption but have limited impact in European populati...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Clarke, T-K, Adams, M J, Davies, G, Howard, D M, Hall, L S, Padmanabhan, S, Murray, A D, Smith, B H, Campbell, A, Hayward, C, Porteous, D J, Deary, I J, McIntosh, A M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Immediate Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622124/
https://ncbi.nlm.nih.gov/pubmed/28937693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.153
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