MTG16 is a tumor suppressor in colitis-associated carcinoma

MTG16 is a member of the myeloid translocation gene (MTG) family of transcriptional corepressors. While MTGs were originally identified in chromosomal translocations in acute myeloid leukemia, recent studies have uncovered a role in intestinal biology. For example, Mtg16(–/–) mice have increased int...

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Udgivet i:JCI Insight
Main Authors: McDonough, Elizabeth M., Barrett, Caitlyn W., Parang, Bobak, Mittal, Mukul K., Smith, J. Joshua, Bradley, Amber M., Choksi, Yash A., Coburn, Lori A., Short, Sarah P., Thompson, Joshua J., Zhang, Baolin, Poindexter, Shenika V., Fischer, Melissa A., Chen, Xi, Li, Jiang, Revetta, Frank L., Naik, Rishi, Washington, M. Kay, Rosen, Michael J., Hiebert, Scott W., Wilson, Keith T., Williams, Christopher S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621889/
https://ncbi.nlm.nih.gov/pubmed/28814670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.78210
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