HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication

Hepatitis C virus (HCV) induces autophagy to promote its replication, including its RNA replication, which can take place on double-membrane vesicles known as autophagosomes. However, how HCV induces the biogenesis of autophagosomes and how HCV RNA replication complex may be assembled on autophagoso...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Wang, Linya, Kim, Ja Yeon, Liu, Helene Minyi, Lai, Michael M. C., Ou, Jing-hsiung James
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621699/
https://ncbi.nlm.nih.gov/pubmed/28931085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006609
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