Simultaneous identification of GSTP1 Ile105→Val105 and Ala114→Val114 substitutions using an amplification refractory mutation systempolymerase chain reactionassay: studies in patients with asthma

BACKGROUND: The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the Ile105→Val105 substitution are associated with the asthma phenotypes of atopy and bronchial hyperresponsiveness (BHR). However, a further p...

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Detalhes bibliográficos
Main Authors: Hemmingsen, Anja, Fryer, Anthony A, Hepple, Michael, Strange, Richard C, Spiteri, Monica A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56208/
https://ncbi.nlm.nih.gov/pubmed/11686891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/rr64
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