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Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)—How Does the Endoplasmic Reticulum Membrane Influence Their Function?

Uridine diphosphate-glucuronosyltransferases (UGTs) are phase 2 conjugation enzymes mainly located in the endoplasmic reticulum (ER) of the liver and many other tissues, and can be recovered in artificial ER membrane preparations (microsomes). They catalyze glucuronidation reactions in various aglyc...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Liu, Yuejian, Coughtrie, Michael W. H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620573/
https://ncbi.nlm.nih.gov/pubmed/28867809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics9030032
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