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Adjuvantation of Pulmonary-Administered Influenza Vaccine with GPI-0100 Primarily Stimulates Antibody Production and Memory B Cell Proliferation

Adjuvants are key components in vaccines, they help in reducing the required antigen dose but also modulate the phenotype of the induced immune response. We previously showed that GPI-0100, a saponin-derived adjuvant, enhances antigen-specific mucosal and systemic antibody responses to influenza sub...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Patil, Harshad P., Herrera Rodriguez, José, de Vries-Idema, Jacqueline, Meijerhof, Tjarko, Frijlink, Henderik W., Hinrichs, Wouter L. J., Huckriede, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620550/
https://ncbi.nlm.nih.gov/pubmed/28749414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines5030019
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