Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

BACKGROUND: Poly-(ADP-Ribose)-Polymerase (PARP) inhibitors are becoming important actors of anti-neoplasic agents landscape, with recent but narrow FDA's approvals for ovarian BRCA mutated cancers and prostatic cancer. Nevertheless, PARP inhibitors are also promising drugs for combined treatmen...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Lesueur, Paul, Chevalier, François, Austry, Jean-Baptiste, Waissi, Waisse, Burckel, Hélène, Noël, Georges, Habrand, Jean-Louis, Saintigny, Yannick, Joly, Florence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620324/
https://ncbi.nlm.nih.gov/pubmed/28978184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19079
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