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PRAS40 signaling in tumor

The proline-rich Akt substrate of 40 kDa (PRAS40) is a substrate of Akt and a component of the mammalian target of rapamycin complex 1 (mTORC1). Locating at the crossroad of the PI3K/Akt pathway and the mTOR pathway, PRAS40 is phosphorylated by growth factors or other stimuli, and regulates the acti...

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Pubblicato in:Oncotarget
Autori principali: Lv, Dan, Guo, Lianying, Zhang, Ting, Huang, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620322/
https://ncbi.nlm.nih.gov/pubmed/28978182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17299
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