Downregulation of miR-99a/let-7c/miR-125b miRNA cluster predicts clinical outcome in patients with unresected malignant pleural mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive tumor with a dismal overall survival (OS) and to date no molecular markers are available to guide patient management. This study aimed to identify a prognostic miRNA signature in MPM patients who did not undergo tumor resection. Whole miRNA profi...

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Vydáno v:Oncotarget
Hlavní autoři: Truini, Anna, Coco, Simona, Nadal, Ernest, Genova, Carlo, Mora, Marco, Dal Bello, Maria Giovanna, Vanni, Irene, Alama, Angela, Rijavec, Erika, Biello, Federica, Barletta, Giulia, Merlo, Domenico Franco, Valentino, Alessandro, Ferro, Paola, Ravetti, Gian Luigi, Stigliani, Sara, Vigani, Antonella, Fedeli, Franco, Beer, David G., Roncella, Silvio, Grossi, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620283/
https://ncbi.nlm.nih.gov/pubmed/28978143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19800
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