DNA repair deregulation in discrete prostate cancer lesions identified on multi-parametric MRI and targeted by MRI/ultrasound fusion-guided biopsy

Prostate cancer is histologically and molecularly heterogeneous. Clinically significant disease is often driven by dominant intra-prostatic lesions (IPLs). Prostate cancers cluster into molecular phenotypes with substantial genetic heterogeneity making pathway-based molecular analysis appealing. MRI...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dulaney, Caleb R., Rais-Bahrami, Soroush, Manna, Debra Della, Gordetsky, Jennifer B., Nix, Jeffrey W., Yang, Eddy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620234/
https://ncbi.nlm.nih.gov/pubmed/28978094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19145
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