Functional dissection of breast cancer risk-associated TERT promoter variants

The multi-cancer susceptibility locus at 5p15.33 includes TERT, encoding the telomerase catalytic subunit. Genome-wide association studies (GWAS) have identified six single nucleotide polymorphisms (SNPs) in the TERT promoter associated with decreased breast cancer risk, although the precise causal...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Helbig, Sonja, Wockner, Leesa, Bouendeu, Annick, Hille-Betz, Ursula, McCue, Karen, French, Juliet D, Edwards, Stacey L, Pickett, Hilda A, Reddel, Roger R, Chenevix-Trench, Georgia, Dörk, Thilo, Beesley, Jonathan
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620167/
https://ncbi.nlm.nih.gov/pubmed/28978027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18226
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