A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy

Bacteria downregulate their ribosomal activity through dimerization of 70S ribosomes, yielding inactive 100S complexes. In Escherichia coli, dimerization is mediated by the hibernation promotion factor (HPF) and ribosome modulation factor. Here we report the cryo-electron microscopy study on 100S ri...

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Publicat a:Nat Commun
Autors principals: Franken, Linda E., Oostergetel, Gert T., Pijning, Tjaard, Puri, Pranav, Arkhipova, Valentina, Boekema, Egbert J., Poolman, Bert, Guskov, Albert
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620043/
https://ncbi.nlm.nih.gov/pubmed/28959045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00718-x
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