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N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton

Regulated intracellular proteostasis, controlled in part by proteolysis, is essential in maintaining the integrity of podocytes and the glomerular filtration barrier of the kidney. We applied a novel proteomics technology that enables proteome-wide identification, mapping, and quantification of prot...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Rinschen, Markus M., Hoppe, Ann-Kathrin, Grahammer, Florian, Kann, Martin, Völker, Linus A., Schurek, Eva-Maria, Binz, Julie, Höhne, Martin, Demir, Fatih, Malisic, Milena, Huber, Tobias B., Kurschat, Christine, Kizhakkedathu, Jayachandran N., Schermer, Bernhard, Huesgen, Pitter F., Benzing, Thomas
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619959/
https://ncbi.nlm.nih.gov/pubmed/28724775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016101119
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