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N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton

Regulated intracellular proteostasis, controlled in part by proteolysis, is essential in maintaining the integrity of podocytes and the glomerular filtration barrier of the kidney. We applied a novel proteomics technology that enables proteome-wide identification, mapping, and quantification of prot...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Rinschen, Markus M., Hoppe, Ann-Kathrin, Grahammer, Florian, Kann, Martin, Völker, Linus A., Schurek, Eva-Maria, Binz, Julie, Höhne, Martin, Demir, Fatih, Malisic, Milena, Huber, Tobias B., Kurschat, Christine, Kizhakkedathu, Jayachandran N., Schermer, Bernhard, Huesgen, Pitter F., Benzing, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619959/
https://ncbi.nlm.nih.gov/pubmed/28724775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016101119
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