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Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma
Primary effusion lymphoma (PEL) is an aggressive B-cell lymphoma with poor prognosis caused by Kaposi’s sarcoma-associated herpesvirus (KSHV). Previous studies have revealed that HIF-1α, which mediates much of the cellular response to hypoxia, plays an important role in life cycle of KSHV. KSHV infe...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5619862/ https://ncbi.nlm.nih.gov/pubmed/28922425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006628 |
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