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Gene selection tool (GST): A R-based tool for genetic disorders based on the sliding-window proportion test using whole-exome sequencing data

Whole-exome sequencing (WES) can identify causative mutations in hereditary diseases. However, WES data might have a large candidate variant list, including false positives. Moreover, in families, it is more difficult to select disease-associated variants because many variants are shared among membe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Sugi, Jung, Minah, Jung, Jaeeun, Park, Kunhyang, Ryu, Jea-Woon, Kim, Jeongkil, Kim, Dae-soo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619773/
https://ncbi.nlm.nih.gov/pubmed/28957403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185514
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