Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4

Platelets have a major role in clotting activation and contribute to the innate immune response during systemic infections. Human platelets contain tissue factor (TF) and express functional Toll-like receptor 4 (TLR4). However, the role of TLR4 in triggering the procoagulant properties of platelets,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Matus, Valeria, Valenzuela, J. Guillermo, Hidalgo, Patricia, Pozo, L. María, Panes, Olga, Wozniak, Aniela, Mezzano, Diego, Pereira, Jaime, Sáez, Claudia G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619753/
https://ncbi.nlm.nih.gov/pubmed/28957360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185431
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