Nf-GH, a glycosidase secreted by Naegleria fowleri, causes mucin degradation: an in vitro and in vivo study

AIM: The aim of this work was to identify, characterize and evaluate the pathogenic role of mucinolytic activity released by Naegleria fowleri. MATERIALS & METHODS: Zymograms, protease inhibitors, anion exchange chromatography, MALDI-TOF-MS, enzymatic assays, Western blot, and confocal microscop...

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Detalhes bibliográficos
Publicado no:Future Microbiol
Main Authors: Martínez-Castillo, Moisés, Cárdenas-Guerra, Rosa Elena, Arroyo, Rossana, Debnath, Anjan, Rodríguez, Mario Alberto, Sabanero, Myrna, Flores-Sánchez, Fernando, Navarro-Garcia, Fernando, Serrano-Luna, Jesús, Shibayama, Mineko
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619013/
https://ncbi.nlm.nih.gov/pubmed/28608712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb-2016-0230
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