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Ipilimumab: from preclinical development to future clinical perspectives in melanoma

The arsenal for the treatment of metastatic melanoma is limited. A new approach to therapy using checkpoint blockade has improved overall survival in this patient population. Ipilimumab a CTLA-4 monoclonal antibody is a first in class drug that has pioneered this revolution. In this review, the auth...

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Detalhes bibliográficos
Publicado no:Future Oncol
Main Authors: Letendre, Paul, Monga, Varun, Milhem, Mohammed, Zakharia, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618953/
https://ncbi.nlm.nih.gov/pubmed/27882779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon-2016-0385
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