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Preparing to read the ubiquitin code: top-down analysis of unanchored ubiquitin tetramers

The characterization of polyubiquitin chains has been an analytical challenge for several decades. It has been shown that anchored and unanchored polyubiquitin chains with different isopeptide linkages and lengths exhibit a wide range of profoundly different cellular functions. However, structure fu...

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Bibliographic Details
Published in:J Mass Spectrom
Main Authors: Lee, Amanda E., Geis-Asteggiante, Lucia, Dixon, Emma K., Miller, Meredith, Wang, Yan, Fushman, David, Fenselau, Catherine
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618806/
https://ncbi.nlm.nih.gov/pubmed/28239975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.3787
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