A Novel CXCR4 antagonist enhances angiogenesis via modifying the ischaemic tissue environment

Endothelial progenitor cells (EPCs) play a capital role in angiogenesis via directly participating in neo‐vessel formation and secreting pro‐angiogenic factors. Stromal cell‐derived factor 1 (SDF‐1) and its receptor CXCR4 play a critical role in the retention and quiescence of EPCs within its niche...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Yan, Xiaoqing, Dai, Xiaozhen, He, Luqing, Ling, Xiao, Shao, Minglong, Zhang, Chi, Wang, Yuehui, Xiao, Jian, Cai, Lu, Li, Xiaokun, Tan, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618675/
https://ncbi.nlm.nih.gov/pubmed/28374486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13150
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