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Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression

N-acetyltransferase 10 (NAT10) has been considered a target for the treatment of human diseases such as cancer and laminopathies; however, its functional role in the biology of melanocytes is questionable. Using a small molecule or small interfering RNA targeting NAT10, we examined the effect of NAT...

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Publicat a:Int J Mol Sci
Autors principals: Oh, Taek-In, Lee, Yoon-Mi, Lim, Beong-Ou, Lim, Ji-Hong
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618573/
https://ncbi.nlm.nih.gov/pubmed/28880216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091924
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