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The Role of Focal Adhesion Kinase in Keratinocyte Fibrogenic Gene Expression

Abnormal skin scarring causes functional impairment, psychological stress, and high socioeconomic cost. Evidence shows that altered mechanotransduction pathways have been linked to both inflammation and fibrosis, and that focal adhesion kinase (FAK) is a key mediator of these processes. We investiga...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Januszyk, Michael, Kwon, Sun Hyung, Wong, Victor W., Padmanabhan, Jagannath, Maan, Zeshaan N., Whittam, Alexander J., Major, Melanie R., Gurtner, Geoffrey C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618564/
https://ncbi.nlm.nih.gov/pubmed/28880199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091915
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