Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered via a Magnetic Nanocarrier

Here, we report the synthesis, characterization, and efficacy study of Fe/Fe(3)O(4)-nanoparticles that were co-labeled with a tumor-homing and membrane-disrupting oligopeptide and the iron-chelator Dp44mT, which belongs to the group of the thiosemicarbazones. Dp44mT and the peptide sequence PLFAERL(...

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Détails bibliographiques
Publié dans:J Funct Biomater
Auteurs principaux: Abayaweera, Gayani S., Wang, Hongwang, Shrestha, Tej B., Yu, Jing, Angle, Kyle, Thapa, Prem, Malalasekera, Aruni P., Maurmann, Leila, Troyer, Deryl L., Bossmann, Stefan H.
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618274/
https://ncbi.nlm.nih.gov/pubmed/28672849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jfb8030023
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