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Coupling TOR to the Cell Cycle by the Greatwall–Endosulfine–PP2A-B55 Pathway

Cell growth and division are two processes tightly coupled in proliferating cells. While Target of Rapamycin (TOR) is the master regulator of growth, the cell cycle is dictated by the activity of the cyclin-dependent kinases (CDKs). A long-standing question in cell biology is how these processes may...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Pérez-Hidalgo, Livia, Moreno, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618240/
https://ncbi.nlm.nih.gov/pubmed/28777780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7030059
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