Deletion of TXNIP Mitigates High-Fat Diet-Impaired Angiogenesis and Prevents Inflammation in a Mouse Model of Critical Limb Ischemia

Background: Previous work demonstrated that high-fat diet (HFD) triggered thioredoxin-interacting protein (TXNIP) and that silencing TXNIP prevents diabetes-impaired vascular recovery. Here, we examine the impact of genetic deletion of TXNIP on HFD-impaired vascular recovery using hind limb ischemia...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Elshaer, Sally L., Mohamed, Islam N., Coucha, Maha, Altantawi, Sara, Eldahshan, Wael, Bartasi, Megan L., Shanab, Ahmed Y., Lorys, Renee, El-Remessy, Azza B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618075/
https://ncbi.nlm.nih.gov/pubmed/28661427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox6030047
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