p16 Methylation was associated with the development, age, hepatic viruses infection of hepatocellular carcinoma, and p16 expression had a poor survival: A systematic meta-analysis (PRISMA)

BACKGROUND: Loss of tumor suppressor gene p16 expression via promoter methylation has been reported in hepatocellular carcinoma (HCC). This meta-analysis was conducted to evaluate the correlation between p16 methylation and HCC. Additionally, we also analyzed the potential prognostic role of p16 met...

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Publicado en:Medicine (Baltimore)
Autores principales: Lv, Xueyou, Ye, Guoliang, Zhang, Xinjun, Huang, Tao
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Health 2017
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4500
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617726/
https://ncbi.nlm.nih.gov/pubmed/28930859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000008106
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