NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

Macrophages are attracted to developing tumors and can participate in immune surveillance to eliminate neoplastic cells. In response, neoplastic cells utilize NF-κB to suppress this killing activity, but the mechanisms underlying their self-protection remain unclear. Here, we report that this dynami...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Ratnam, Nivedita M., Peterson, Jennifer M., Talbert, Erin E., Ladner, Katherine J., Rajasekera, Priyani V., Schmidt, Carl R., Dillhoff, Mary E., Swanson, Benjamin J., Haverick, Ericka, Kladney, Raleigh D., Williams, Terence M., Leone, Gustavo W., Wang, David J., Guttridge, Denis C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617672/
https://ncbi.nlm.nih.gov/pubmed/28891811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91561
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