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TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer

Expression pattern and biological roles of TRIM22 remains unknown in most human cancers. The present study aims to discover its clinical significance and function in human non-small cell lung cancer (NSCLC). Immunohistochemistry was used to examine TRIM22 expression in 126 cases of NSCLC specimens....

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Liu, Li, Zhou, Xiao-Ming, Yang, Fang-Fei, Miao, Yuan, Yin, Yan, Hu, Xue-Jun, Hou, Gang, Wang, Qiu-Yue, Kang, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617487/
https://ncbi.nlm.nih.gov/pubmed/28977927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18911
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