Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway

We investigated the effects of endoplasmic reticulum stress (ERS) on autophagy, proliferation, apoptosis, and drug resistance in multiple myeloma (MM). MM patients enrolled in our study (n = 268) were classified into sensitive and resistant groups based on chemotherapy efficacy, and their serum leve...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fu, Yun-Feng, Liu, Xiao, Gao, Meng, Zhang, Ya-Nan, Liu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617409/
https://ncbi.nlm.nih.gov/pubmed/28977849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17862
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