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Decreased WWOX expression promotes angiogenesis in osteosarcoma

WWOX (WW domain-containing oxidoreductase) is known to be an important tumor suppressor in cancer. In this study, we used samples from 201 osteosarcoma patients to investigate the effects of WWOX on angiogenesis and invasion. WWOX levels were negatively correlated with RUNX2 and VEGF levels, but wer...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wen, Jia, Xu, Zongchao, Li, Jiazhen, Zhang, Yingqiang, Fan, Wenzhe, Wang, Yu, Lu, Mingjian, Li, Jiaping
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617394/
https://ncbi.nlm.nih.gov/pubmed/28977834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17126
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