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The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases

Associations between epigenetic alterations and disease status have been identified for many diseases. However, there is no strong evidence that epigenetic alterations are directly causal for disease pathogenesis. In this study, we combined SNP and DNA methylation data with measurements of protein b...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Ahsan, Muhammad, Ek, Weronica E., Rask-Andersen, Mathias, Karlsson, Torgny, Lind-Thomsen, Allan, Enroth, Stefan, Gyllensten, Ulf, Johansson, Åsa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617224/
https://ncbi.nlm.nih.gov/pubmed/28915241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007005
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