Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections

Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures driving DENV microevolution within human hosts (intrahost) remain unknown. We employed a whole-genome segmented amplification approach coupled with...

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Vydáno v:Cell Host Microbe
Hlavní autoři: Parameswaran, Poornima, Wang, Chunling, Trivedi, Surbhi Bharat, Eswarappa, Meghana, Montoya, Magelda, Balmaseda, Angel, Harris, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616187/
https://ncbi.nlm.nih.gov/pubmed/28910637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.08.003
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