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New roles for Dicer in the nucleolus and its relevance to cancer
The nucleolus is a distinct compartment of the nucleus responsible for ribosome biogenesis. Mis-regulation of nucleolar functions and of the cellular translation machinery has been associated with disease, in particular with many types of cancer. Indeed, many tumor suppressors (p53, Rb, PTEN, PICT1,...
Guardat en:
| Publicat a: | Cell Cycle |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5616133/ https://ncbi.nlm.nih.gov/pubmed/28846478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1361568 |
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