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Probing Membrane Receptor–Ligand Specificity with Surface- and Tip- Enhanced Raman Scattering

[Image: see text] The specific interaction between a ligand and a protein is a key component in minimizing off-target effects in drug discovery. Investigating these interactions with membrane protein receptors can be quite challenging. In this report, we show how spectral variance observed in surfac...

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Bibliografski detalji
Izdano u:Anal Chem
Glavni autori: Xiao, Lifu, Bailey, Karen A., Wang, Hao, Schultz, Zachary D.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2017
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616087/
https://ncbi.nlm.nih.gov/pubmed/28805059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b01796
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