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Basal ganglia atrophy in prodromal Huntington’s disease is detectable over one year using automated segmentation

BACKGROUND: Future clinical trials of neuroprotection in prodromal Huntington’s (known as preHD) require sensitive in vivo imaging biomarkers to track disease progression over the shortest period. Since basal ganglia atrophy is the most prominent structural characteristic of Huntington’s pathology,...

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Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Majid, DS Adnan, Aron, Adam R, Thompson, Wesley, Sheldon, Sarah, Hamza, Samar, Stoffers, Diederick, Holland, Dominic, Goldstein, Jody, Corey-Bloom, Jody, Dale, Anders M
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615846/
https://ncbi.nlm.nih.gov/pubmed/21932302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23912
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