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Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis

BACKGROUND: Angiostrongylus cantonensis is an important causative agent of eosinophilic meningitis and eosinophilic meningoencephalitis in humans. Previous studies have shown that the Sonic hedgehog (Shh) signaling pathway may reduce cell apoptosis by inhibiting oxidative stress in A. cantonensis in...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Chen, Kuang-Yao, Wang, Lian-Chen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615811/
https://ncbi.nlm.nih.gov/pubmed/28950910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-2385-0
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