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Development of an antibiotic marker-free platform for heterologous protein production in Streptomyces

BACKGROUND: The industrial use of enzymes produced by microorganisms is continuously growing due to the need for sustainable solutions. Nevertheless, many of the plasmids used for recombinant production of proteins in bacteria are based on the use of antibiotic resistance genes as selection markers....

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Sevillano, Laura, Díaz, Margarita, Santamaría, Ramón I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615484/
https://ncbi.nlm.nih.gov/pubmed/28950904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0781-y
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