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Integrins as Therapeutic Targets: Successes and Cancers
Integrins are transmembrane receptors that are central to the biology of many human pathologies. Classically mediating cell-extracellular matrix and cell-cell interaction, and with an emerging role as local activators of TGFβ, they influence cancer, fibrosis, thrombosis and inflammation. Their ligan...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5615325/ https://ncbi.nlm.nih.gov/pubmed/28832494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9090110 |
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