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Determination of the absolute configuration of compounds bearing chiral quaternary carbon centers using the crystalline sponge method

Determination of the absolute configuration of chiral tetra-substituted carbon centers is one of the most taxing steps in the enantioselective construction of this structural motif in asymmetric synthesis. Here, we demonstrate that the crystalline sponge method provides an effective way to crystallo...

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Publicado en:Chem Sci
Main Authors: Sairenji, Shiho, Kikuchi, Takashi, Abozeid, Mohamed Ahmed, Takizawa, Shinobu, Sasai, Hiroaki, Ando, Yuichiro, Ohmatsu, Kohsuke, Ooi, Takashi, Fujita, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615217/
https://ncbi.nlm.nih.gov/pubmed/28970900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01524k
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