Depsidones inhibit aromatase activity and tumor cell proliferation in a co-culture of human primary breast adipose fibroblasts and T47D breast tumor cells

Naturally occurring depsidones from the marine fungus Aspergillus unguis are known to have substantial anti-cancer activity, but their mechanism of action remains elusive. The purpose of this study was to examine the anti-aromatase activity of two common depsidones, unguinol and aspergillusidone A,...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Chottanapund, Suthat, Van Duursen, M.B.M., Zwartsen, Anne, Timtavorn, Supatchaya, Navasumrit, Panida, Kittakoop, Prasat, Sureram, Sanya, Ruchirawat, Mathuros, Van den Berg, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615129/
https://ncbi.nlm.nih.gov/pubmed/28959637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2017.03.004
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