TRIM25 in the Regulation of the Antiviral Innate Immunity

TRIM25 is an E3 ubiquitin ligase enzyme that is involved in various cellular processes, including regulation of the innate immune response against viruses. TRIM25-mediated ubiquitination of the cytosolic pattern recognition receptor RIG-I is an essential step for initiation of the intracellular anti...

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Udgivet i:Front Immunol
Main Authors: Martín-Vicente, María, Medrano, Luz M., Resino, Salvador, García-Sastre, Adolfo, Martínez, Isidoro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614919/
https://ncbi.nlm.nih.gov/pubmed/29018447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01187
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